Evaluating opioid and analgesic regimens for post-operative pain management in gynecological surgery: A comparative...

Effective post-operative pain control remains a crucial component of recovery following gynecological surgery, with opioid-related adverse effects posing significant clinical challenges. Multimodal analgesia, integrating multiple drug classes acting through different mechanisms, offers a promising approach to enhance pain relief while reducing opioid dependency. Hence, this prospective comparative study included 150 patients undergoing elective gynecological surgeries divided into two groups: Group A received opioid-based analgesic regimens and Group B was treated using multimodal analgesia combining opioids and non-opioid agents. Pain intensity was assessed at scheduled post-operative intervals using the Visual Analog Scale (VAS), alongside documentation of adverse effects. Thus, we show that multimodal analgesic regimens provide safer and more effective post-operative analgesia than traditional opioid-based approaches for gynecological surgical patients.