Concentration-dependent antimicrobial effects of two mouthwashes on key periodontal pathogens: An in vitro study

Periodontal diseases, caused by pathogenic dental plaque biofilm, are often treated with chlorhexidine, but its long-term use can lead to undesirable side effects. Therefore, it is of interest to compare the antimicrobial efficacy of two herbal mouthwashes, Oralife and Ora-T, against periodontal pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans using the disc diffusion method. Results showed that Oralife exhibited significantly larger zones of inhibition than Ora-T at all tested concentrations. No inhibitory effect was observed at the lowest concentration. Thus, we show Oralife's potential as a more effective herbal alternative for periodontal therapy.