Machine learning based prediction of gestational diabetes mellitus using early pregnancy biomarkers and clinical data

Gestational diabetes mellitus (GDM) is a common pregnancy-related condition that can lead to significant maternal and neonatal complications, but conventional screening methods often delay diagnosis. Therefore, it is of interest to develop a machine learning model for early prediction of GDM using first-trimester biomarkers and clinical data. Hence, a prospective study of 100 pregnant women was conducted and various machine learning algorithms were trained to predict GDM. The random forest model showed the best performance with an accuracy of 86% and an AUC of 0.90. Thus, we show the potential of machine learning in enabling early prediction and timely intervention for GDM, improving maternal and neonatal outcomes.