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Updated: Aug 29, 2026

Super-Resolution Imaging and Shared Management: A Protocol for Confocal Microscopy with Multiplex Detection
Published on: February 24, 2026
Digital infrastructure to support and share daily high-throughput experimental materials research
Lena A Mittmann1, Hampus Nässtrom2, Eugène Bertin1
1National Centre for Nano Fabrication and Characterization (DTU Nanolab), Technical University of Denmark, 2800 Kongens Lyngby, Denmark. mittma@dtu.dk.
Abstract:
High-throughput and autonomous experimentation generate complex, heterogeneous datasets whose reuse, large-scale analysis, and linking to data from first-principles calculations remain challenging. Here, we report on an operational deployment of the open-source NOMAD Oasis data infrastructure as a digital backbone for daily high-throughput experimental work in a materials discovery group at DTU Nanolab. The customized platform supports the complete experimental workflow in a thin-film laboratory, linking physical inventory items, automated synthesis logs, high-throughput characterization data, and cloud-based analysis within a unified data model. The platform preserves full sample provenance across multi-step workflows and uses unified sample coordinates to enable direct cross-technique correlation. We demonstrate the capabilities of the platform on a combined experimental-computational project centered on phosphosulfide thin-film libraries. The data consists of 12 000 experimental samples acquired during routine operation over 18 months, complemented by more than 800 first-principles calculations - all managed in a unified data platform available at https://nomad.nanolab.dtu.dk/nomad-oasis/gui/search/combinatorial-samples. We show how an open, extensible data infrastructure system supports reproducible workflows, scalable analysis, and long-term data reuse.

