Related Experiment Video
Updated: Aug 30, 2026
Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
The First Reported Transcatheter Closure of Patent Ductus Venosus Using the LifeTech™ Konar-MFO VSD Occluder in an
Introduction:
Congenital portosystemic shunts (CPSS) are rare vascular anomalies that can lead to hyperammonemia and liver dysfunction.
Case Presentation:
A 1-month-old infant was diagnosed with incidental patent ductus venosus (PDV) and a focal nodular hyperplasia-like liver nodule. Laboratory tests revealed hyperammonemia (192 µmol/L) and cholestasis. Imaging confirmed a 7.8-mm shunt connecting the left portal vein to the inferior vena cava. Urgent transcatheter closure was performed via the right jugular vein using a 12/10-mm LifeTech™ Konar-MFO occluder. Post-procedural imaging showed complete shunt occlusion, and ammonia levels rapidly decreased to 71.8 µmol/L. Cholestasis improved, and the patient was discharged without complications.
Conclusion:
This report describes the first global use of the Konar-MFO device for PDV closure. Transcatheter embolization using this device is a safe and effective minimally invasive treatment for symptomatic PDV in young infants.
