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Updated: Aug 30, 2026

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
Published on: October 31, 2012
Lab resource: single cell line generation of an induced pluripotent stem cell line UJSi006-A from a patient with
Dingqi Zhang1, Yupeng Wang1, Bonan Chen1
1Neurobiology & Mitochondrial Key Laboratory, Effective & Toxicity Monitoring Innovative Practice Center for Food Pharmaceutical Specialty, School of Pharmacy, Jiangsu University, Zhenjiang 212013, PR China.
Abstract:
Ultra-treatment-resistant schizophrenia (UTRS) is the most severe subtype of treatment refractoriness, with persistent symptoms despite clozapine use. Here, we report the generation of a human induced pluripotent stem cells (iPSCs) line, UJSi006-A, derived from peripheral blood mononuclear cells (PBMCs) of a 31-year-old female patient with UTRS. The iPSC line displayed typical human pluripotent stem cell morphology, a normal karyotype, expression of pluripotency markers, and the capacity to differentiate into derivatives of all three germ layers in vitro. This iPSC resource provides a cellular platform for investigating disease mechanisms and treatment resistance in schizophrenia.
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