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Updated: Aug 30, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
Published on: March 11, 2017
Dual-energy CT-generated bone marrow edema maps improve reader confidence without changing fracture detection rates
Boniface Yarabe1, William R Walter1, Shana G Neumann1
1Department of Radiology, NYU Langone Health, 660 First Ave, 3rd Fl, New York, NY, 10016, USA.
Objective:
To retrospectively evaluate the diagnostic utility of dual-energy computed tomography (DECT) virtual non-calcium bone marrow edema (BME) maps in the assessment of osseous pelvic trauma compared to conventional CT. In addition to fracture detection rates, we sought to determine the DECT effect on reader diagnostic confidence and follow-up recommendations.
Materials And Methods:
Three radiologists performed independent retrospective reviews of 92 consecutive pelvic CTs for the presence of fractures, without the use of DECT-generated BME maps. Following a washout period of ≥ 4 weeks, the cases were re-reviewed with the addition of DECT BME maps. Comparison of fracture detection rates, frequency of "indeterminate" reads, reader confidence ratings, and follow-up imaging recommendations were performed using McNemar's test and mixed-effects logistic regressions. Mixed-effect models were utilized to assess the effect of DEXA-derived patient bone mineral density, when available, on fracture detection rates.
Results:
The use of DECT BME maps resulted in higher pooled reader diagnostic confidence, with a mean 0.19 increase on a 5-point Likert scale (p < 0.001). There was, however, no statistically significant difference in fracture detection rates for readers utilizing DECT versus conventional CT alone, with similar rates of "indeterminate" interpretations between the groups. For patients with recent DEXAs (n = 27), DECT was not associated with change in fracture detection rates among patients with osteoporosis or osteopenia. Readers recommended follow-up imaging more frequently in cases interpreted with DECT, but this effect was not significant (p = 0.266).
Conclusion:
When interpreting pelvic CT for trauma, DECT-generated BME maps increased diagnostic confidence without changing detection rates.

