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Is there a limit to limitations? A proposal for structured limitations reporting in scientific manuscripts
Christos G Tsagkaris1,2, Irem Sevik3
1Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Abstract:
Reporting studies limitations is essential for transparent interpretation. While reporting guidelines such as CONSORT, STROBE, PRISMA mandate disclosure of limitations, no widely adopted framework standardizes how these are reported in a structured and comparable format. In practice, limitations sections often extend over several paragraphs reiterating predictable design-related constraints. This limits comparability, contributes to inefficiency and may overshadow genuine study-specific considerations. We propose a semi-structured checklist combining standardized limitation domains with a concise narrative component. This approach aims to ensure minimum systematic disclosure while preserving critical interpretation. Structured reporting may improve clarity, comparability, and enable meta-research on limitations across studies. Consensus-based refinement and pilot implementation are warranted to evaluate feasibility and impact.
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