A gene set collection of human RBP target genes

RNA binding proteins (RBPs) are key post-transcriptional regulators controlling every aspect of the RNA life cycle from synthesis to decay. We extracted RBP target genes from publicly available enhanced cross-linking and immuno-precipitation followed by sequencing (eCLIP-seq) data of 168 RBPs and assembled a gene set collection that can be used to examine gene lists for enriched RBP targets via functional enrichment analysis methods like over-representation analysis (ORA), gene set enrichment analysis (GSEA) or gene set variation analysis (GSVA).