Related Experiment Video
Updated: Sep 1, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
[Advances and prospects of hemostatic strategies in hepatic surgery]
1Department of General Surgery,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,China.
The liver is characterized by abundant blood supply and intricate anatomical architecture,rendering intraoperative and postoperative hemorrhage a primary clinical challenge. Conventional compression and suture ligation fail to enable precise perioperative hemorrhage prediction. Driven by the integration of precision medicine,artificial intelligence,and biomaterials,hemostatic strategies are undergoing a paradigm shift from passive compression to precise targeted intervention. This paper systematically reviews advances and future perspectives in hemostatic strategies for hepatic surgery. Preoperative individualized intervention is achieved via tranexamic acid prophylaxis,portal vein embolization,and radiological assessment; intraoperatively,Peng's curettage-suction technique enhances hemorrhage control; postoperatively,tiered "pharmacological-interventional-surgical" management allows proactive whole-course hemostatic regulation. Looking ahead,nano-drug delivery systems coupled with artificial intelligence closed-loop frameworks will facilitate the integrated development of hemostasis,liver regeneration promotion,and postoperative recurrence inhibition.
The liver is characterized by abundant blood supply and intricate anatomical architecture,rendering intraoperative and postoperative hemorrhage a primary clinical challenge. Conventional compression and suture ligation fail to enable precise perioperative hemorrhage prediction. Driven by the integration of precision medicine,artificial intelligence,and biomaterials,hemostatic strategies are undergoing a paradigm shift from passive compression to precise targeted intervention. This paper systematically reviews advances and future perspectives in hemostatic strategies for hepatic surgery. Preoperative individualized intervention is achieved via tranexamic acid prophylaxis,portal vein embolization,and radiological assessment; intraoperatively,Peng's curettage-suction technique enhances hemorrhage control; postoperatively,tiered "pharmacological-interventional-surgical" management allows proactive whole-course hemostatic regulation. Looking ahead,nano-drug delivery systems coupled with artificial intelligence closed-loop frameworks will facilitate the integrated development of hemostasis,liver regeneration promotion,and postoperative recurrence inhibition.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Introduction to Hemostasis
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Venous Thrombosis III: Interprofessional Care
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
