Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Conjunctival capillary fragility: a preliminary study.

S R Chandra, J W McMeel, R A Field

Archives of Ophthalmology (Chicago, Ill. : 1960)

|April 1, 1979

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

COVID-19 Vaccine-triggered Relapsing Immune Dysregulation: An Observational Study with Four-year Follow-up.

Annals of neurosciences·2026

Same author

Erratum: Flavonoids: an overview - CORRIGENDUM in Figure 1.

Journal of nutritional science·2025

Same author

Using the POD sampler for quantitative diffusive (passive) monitoring of volatile and very volatile organics in ambient air: Sampling rates and analytical performance.

Environment international·2023

Same author

Spectrum of Clinical and Imaging Characteristics of 48 X-Linked Adrenoleukodystrophy Patients: Our Experience from a University Hospital.

Neurology India·2022

Same author

Disorders of Tetrahydrobiopterin Metabolism: Experience from South India.

Metabolic brain disease·2022

Same author

Systemic inflammatory syndrome in COVID-19-SISCoV study: systematic review and meta-analysis.

Pediatric research·2021

Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

See all related articles

Diabetic retinopathy patients show increased conjunctival capillary fragility (CCF) compared to healthy individuals. Skin capillary fragility (SCF) did not differ between the groups, suggesting CCF is a specific indicator in diabetic retinopathy.

Area of Science:

Ophthalmology
Diabetology
Vascular Biology

Background:

Diabetic retinopathy is a microvascular complication of diabetes.
Capillary fragility may play a role in the pathogenesis of diabetic retinopathy.

Purpose of the Study:

To investigate conjunctival capillary fragility (CCF) and skin capillary fragility (SCF) in patients with diabetic retinopathy.
To compare CCF and SCF between diabetic retinopathy patients and normal subjects.

Main Methods:

Utilized a negative-pressure suction cup method to assess capillary fragility.
Studied 25 normal subjects and 38 patients diagnosed with diabetic retinopathy.

Main Results:

Conjunctival capillary fragility (CCF) was significantly elevated in diabetic retinopathy patients (P < .001).

Related Experiment Videos

No significant difference in skin capillary fragility (SCF) was observed between the diabetic retinopathy group and the normal group.

Conclusions:

Conjunctival capillary fragility is significantly higher in individuals with diabetic retinopathy.
Skin capillary fragility does not appear to be affected in diabetic retinopathy.
CCF may serve as a potential biomarker for microvascular changes in diabetic retinopathy.