Exploring the Interplay of Movement Dispersion, Sleep, and Quality of Life Among Men With and Without HIV

Pure and total movement dispersion are measures of the spread of physical activity (PA) across the day, without (pure) and with (total) intensity. Men with HIV (MWH) tend to have lower PA, more sedentary behavior, and poorer sleep quality and quality of life than men without HIV (MWOH). This study explores the relationship of pure and total movement dispersion with sleep quality, total sleep time, and quality-of-life (QoL) among MWH and MWOH. This study was a secondary analysis from the MACS/WIHS Combined Cohort Study (MWCCS). Participants wore an ActiGraph and an Actiwatch accelerometer on their wrist for 7 days to measure PA and sleep and completed the Pittsburgh Sleep Quality Index and the Medical Outcomes Study Short Form. Spearman's Rank Correlation and multivariable linear regressions were used to analyze relationships among variables. 594 participants were included (M_age = 58.1, 55% MWH, 62% White). MWH demonstrated higher pure (Z = - 3.893, p < 0.001) and total movement dispersion (Z = - 3.826, p < 0.001) than MWOH. MWH reported worse sleep quality (t = - 3.030, p=.003) and general QoL (t = 2.942, p = 0.003), yet better health compared to last year (t = - 2.557, p = 0.011) than MWOH. Pure movement dispersion was significantly associated with less total sleep time (B = - 1.227, p < 0.001), and total movement dispersion was significantly associated with a higher global general health (B = 7.498, p = 0.044). Movement across the day, with and without regard to intensity, warrants exploration on whether the way an individual achieves PA is dispersed matters more than the accumulated minutes.