Related Experiment Video
Updated: Sep 2, 2026
Assessing Intracardiac Vortices with High Frame-Rate Echocardiography-Derived Blood Speckle Imaging in Newborns
Published on: December 22, 2023
Observed pre-intervention and non-intervention ventricular growth trajectories in neonates with severe
Garrett Gianneschi1, Michael Lance Christian2, Hira Arif3
1Department of Neurology, Division of Child Neurology, Rutgers New Jersey Medical School, Newark, NJ, USA. gbg30@rutgers.edu.
Background:
Post-hemorrhagic ventricular dilation (PHVD) after severe intraventricular hemorrhage (SIVH) remains incompletely characterized.
Objective:
To quantify ventricular expansion after SIVH and explore associations with bilateral hemorrhage burden and mortality.
Methods:
We retrospectively reviewed 43 neonates with SIVH-associated PHVD cared for in a single NICU from 2010 to 2025. Serial cranial ultrasounds were measured for ventricular index (VI) and anterior horn width (AHW). Post-intervention measurements were censored. An exploratory bilateral hemorrhage-burden score summed maximum right and left IVH grades.
Results:
VI and AHW increased significantly with PMA, each at 0.105 mm/day. High composite IVH score (7-8) was associated with faster VI and AHW expansion than low score (3-6), and with higher mortality.
Conclusions:
Ventricular enlargement progressed approximately linearly during observed pre-intervention/non-intervention follow-up. Bilateral hemorrhage-burden scoring may improve risk stratification, but findings are exploratory.
