Related Experiment Video
Updated: Sep 2, 2026

Automated Joint Space Detection Improves Bone Segmentation Accuracy
Published on: November 28, 2025
SAM3-AgeSeg: an adaptive segmentation model for bone tumors in the aging population
Fang Zhang1, Xiaoling Yuan1, Hongxia Song1
1Department of Orthopedics, Jinling Hospital, Affiliated Hospital of Medical School Nanjing University, Nanjing, China.
Background:
Accurate segmentation of bone tumors from X-ray images is crucial for clinical diagnosis and treatment planning. However, elderly patients pose a significant challenge to general-purpose segmentation models.
Methods:
To address this aging-related medical challenge, we propose SAM3-AgeSeg, an adaptive segmentation model specifically designed for the aging population. Built on the powerful foundation model SAM3, our approach uses a lightweight fine-tuning technique, Low-Rank Adaptation (LoRA), to efficiently learn and adapt to the imaging characteristics of elderly bones.
Results:
We conducted a systematic evaluation of the public BTXRD bone tumor X-ray dataset. The experimental results demonstrate that SAM3-AgeSeg outperforms existing state-of-the-art methods in overall segmentation accuracy and exhibits superior boundary segmentation robustness, particularly for a subset of elderly patients.
Discussion:
This study validates the effectiveness of adaptive strategies in enhancing the performance of medical image analysis for aging-related challenges, offering a potential research direction for further investigation into age-adaptive medical image segmentation.
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