Related Experiment Video
Updated: Sep 3, 2026

14:04
Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
Published on: August 26, 2011
Indole-AhR signaling shapes emotional regulation
1Department of Pediatrics, Neonatology Division, University of Minnesota, Minneapolis, MN 55455, USA.
Cell Reports
|September 1, 2026
Abstract:
Wang et al. identify a gut-brain pathway in which loss of the commensal bacterium Alistipes shahii reduces indole production, prevents hippocampal indole-AhR signaling, and drives anxiety and depression behaviors in patients and mouse models of irritable bowel syndrome.1.
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