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Updated: Sep 3, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Staphylococcus aureus Skin and Soft Tissue Infections
Nirusha A Abeydeera-Keshmiri1, Loren G Miller2
1Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance, CA, USA.
Abstract:
Skin and soft tissue infections are common ambulatory infections. Among purulent (suppurative) skin infections, Staphylococcus aureus is responsible for the vast majority. Incision and drainage is a critical part of treatment and adjunctive antibiotics further increase cure rates. Given the rise of antibiotic-resistant S aureus, empiric antibiotics should include coverage for local circulating S aureus strains. Treatment duration is typically 7 days after surgical drainage, assuming adequate clinical response. This article summarizes diagnosis, surgical, and antibiotic management of S aureus skin infections.
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