Related Experiment Video
Updated: Sep 3, 2026
14:23
A Yeast 2-Hybrid Screen in Batch to Compare Protein Interactions
Published on: June 6, 2018
A Yeast Two-Hybrid Assay to Develop Optogenetic Tools for Controlling Protein-Protein Interactions
Ryan M Woloschuk1, G Andrew Woolley2
1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Methods in Molecular Biology (Clifton, N.J.)
|September 2, 2026
Abstract:
Yeast two hybrid (Y2H) assays serve as powerful platforms for the detection and engineering of protein-protein interactions. Here, we describe a strategy for using Y2H-based screening to assess and develop optogenetic tools based on light-controlled protein-protein interactions.
