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Updated: Sep 3, 2026

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source
10:32

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source

Published on: December 6, 2017

Generation of Diversely Functionalized DNA Libraries Using Ligase-Catalyzed Oligonucleotide Polymerization (LOOPER)

Natalie Khamissi1, Luca Rustico1, Ryan Hili2

  • 1Department of Chemistry, Centre for Research on Biomolecular Interactions, York University, Toronto, ON, Canada.

Methods in Molecular Biology (Clifton, N.J.)
|September 2, 2026
PubMed

Keywords:
AptamersCombinatorial libraryDNA templatedLigationModified nucleic acids

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