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Updated: Sep 3, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
Published on: May 30, 2017
[Nontoxigenic Vibrio cholerae O1 bacteraemia and cholangitis in a returning traveller from Sri Lanka]
Marie Thaarup Skov1, Kasper Lenni Andersen2, Hans Linde Nielsen1
1Klinisk Mikrobiologisk Afdeling, Aalborg Universitetshospital.
Abstract:
Vibrio cholerae, typically associated with cholera, rarely causes invasive disease. This case report describes a 59-year-old man with pancreatectomy, splenectomy and diabetes, admitted with nontoxigenic V. cholerae O1 bacteraemia after returning from Sri Lanka, with suspected exposure, including contaminated well water. He presented with fever, upper abdominal pain, and elevated inflammatory, liver, and biliary markers. CT findings and clinical history raised suspicion of cholangitis. Targeted ciprofloxacin led to full recovery. This case highlights the invasive potential of nontoxigenic V. cholerae O1.
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