Related Experiment Video
Updated: Sep 3, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Squamous Cell Carcinoma Developing from an Epidermal Inclusion Cyst on the Buttock
1From the Plastic and Reconstructive Unit, Department of Surgery, Khon Kaen Hospital, Khon Kaen, Thailand.
Abstract:
Epidermal inclusion cysts of the skin rarely undergo malignant transformation into squamous cell carcinoma. We present a case of cutaneous squamous cell carcinoma in a 68-year-old male patient who exhibited clinical features resembling an infected epidermal inclusion cyst on the buttock. Presenting symptoms included rapid growth of the mass, tenderness, and purulent drainage. Although symptoms commonly indicate infection, underlying malignancy must remain a differential consideration. Definitive diagnosis requires histopathologic confirmation. The patient underwent wide excision of the mass and left inguinal node dissection, with the resultant defect covered by a posterior thigh flap. Wide local excision with appropriate margins remains the recommended treatment to ensure complete tumor clearance and minimize the risk of recurrence and pathological analysis essential for definitive diagnosis.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Clinical Applications of Epidermal Stem Cells
Renewal of Skin Epidermal Stem Cells
Healing II: Complications
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Cancer Cell Migration through Invadopodia