Related Experiment Video
Updated: Sep 3, 2026

Multi-Locus Sequencing for Strain Typing of Toxoplasma gondii
Published on: May 26, 2026
First draft genome sequence of the emerging sexually transmitted dermatophyte Trichophyton mentagrophytes genotype
Charlotte Reid1, Mohamed Adnan Asif Ali2, Lara Saivanya2
1Bristol Sequencing Lab, UK Health Security Agency, Bristol, UK.
Abstract:
Trichophyton mentagrophytes ITS-genotype VII (TMVII) is a globally emerging sexually transmitted dermatophyte causing severe skin infections characterised by painful, pustular lesions on the face, public area, genitalia, and trunk. To inform the prevention efforts, we present the first draft genomes of four TMVII isolates obtained from patients in the United Kingdom diagnosed between 2021 and 2025. We performed whole-genome sequencing and phylogenetic analysis based on single-nucleotide polymorphisms. We analysed the genetic relatedness of four TMVII isolates collected from UK patients, two had travel links to Spain and the Middle East. Two further isolates including Trichophyton mentagrophytes ITS-genotype I/II obtained from a canine infection in the UK in 2025 and Trichophyton indotineae were sequenced for contextual analysis. We confirm that the TMVII strains studied here represent a highly clonal population, distinct from both zoophilic T. mentagrophytes genotype I/II, and anthropophilic T. indotineae.
Related Concept Videos
Trichomoniasis
Human Virome
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Phylum Microsporidia

