Turkish Translation, Validation, and Clinical Utilization of the Peyronie's Disease Questionnaire

This study aimed to adapt the peyronie's disease (PD) questionnaire into Turkish, psychometrically evaluate its validity, and explore its correlations with patient demographics and disease-specific characteristics.

The PD questionnaire (PDQ) is a 15-item, self-administered, disease-specific, and multidimensional tool developed to quantify the psychosexual symptoms of PD. This observational study enrolled 95 patients from four healthcare centers in Türkiye. Following translation according to the consensus-based standards for the selection of health measurement instruments, all participants were asked to complete the PDQ during two separate visits. The test-retest reliability of the PDQ and the internal consistency of its subscales were assessed.

The intraclass correlation coefficients were 0.96, 0.95, and 0.98 for the psychological and physical symptoms, symptom bother, and penile pain subscales, respectively. Exploratory factor analysis was conducted to evaluate construct validity. The factor analysis revealed a three-factor structure, explaining 70.34% of the total variance. A penile curvature angle >60° was associated with PDQ symptom scores and International Index of Erectile Function-5 scores (p = 0.047 and p = 0.001, respectively). A body mass index <25 kg/m² and the absence of comorbidities were also associated with PDQ scores.

The Turkish translation and validation of the PDQ were found to be a reliable and useful assessment tool for Turkish individuals with PD. The introduction of the Turkish PDQ may facilitate treatment initiation and follow-up by providing a more reliable and comprehensive evaluation of patients with PD.

The study was registered at clinicaltrials.gov after ethical approval (NCT06621420; https://clinicaltrials.gov/study/NCT06621420).