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Updated: Sep 4, 2026

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
06:00

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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

Chen Chu1, Shanshan Zheng1, Ning Mitchell2

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.

Molecular Cell
|September 2, 2026
PubMed

Keywords:
BRD4CDK2antigen cross-presentationcancercyclin Edendritic cellsimmune checkpoint blockadeimmunotherapy resistanceinterferon-stimulated genestranscriptional regulation

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