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Association Between Changes in Serum N-Terminal Pro B-Type Natriuretic Peptide Levels and All-Cause and
Asahi Kato1,2, Emi Oishi2,3,4, Akihiro Maezono1,2
1Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University.
Background:
Few epidemiological studies have investigated the association between changes in serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and mortality in the general Asian population.
Methods And Results:
We followed 2,703 community-dwelling Japanese residents aged ≥40 years who had serum NT-proBNP concentrations measured in both 2002-2003 and 2007-2008 over a median period of 10.3 years. Changes in NT-proBNP were categorized as decreasing (change ≤-25%), no change (-25%
Conclusions:
Changes in serum NT-proBNP concentrations may indicate mortality risk in a community-dwelling Asian population.
