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Updated: Sep 4, 2026

Methods for the Study of Regeneration in Stentor
Published on: June 13, 2018
Socket regeneration using a composite regenerative matrix: A simplified clinical workflow with a 5-year follow-up
Chi-Shan Tseng1,2, Ming-Ko Li3,4, Cheng-Chia Yu1,5,6
1Institute of Oral Sciences, Chung Shan Medical University, Taichung, Taiwan.
Abstract:
Alveolar ridge remodeling following tooth extraction remains a clinical challenge in implant dentistry, particularly in the esthetic zone where dimensional stability of hard and soft tissues is critical for subsequent implant placement. This short communication describes a simplified clinical workflow for socket regeneration using a composite regenerative matrix (CRM) composed of concentrated growth factor (CGF), autologous fibrinogen glue (AFG), and freeze-dried bone allograft (FDBA). The technique was applied following atraumatic extraction in a single maxillary esthetic-zone case. Clinical and radiographic observations were documented for up to 5 years. Healing was uneventful, and cone-beam computed tomography performed at 3 months demonstrated qualitative socket fill and preservation of ridge contour. Implant placement was subsequently performed using a digitally guided approach. Radiographic follow-up at 1 and 5 years demonstrated stable peri-implant bone levels and maintained buccal plate morphology. The results suggest that CRM provides a simplified, biologically integrated, and predictable workflow for socket regeneration, particularly suitable for esthetic-zone applications requiring long-term dimensional stability.
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