A scientometric study on research trends and characteristics of lymphoma involving the oral cavity

Oral manifestations may present as the first and only sign of lymphoma that primarily affect the oral mucosa, gingiva, and salivary glands. The purpose of this study was to analyze the scientometric characteristics and research trends of lymphoma involving the oral cavity.

All the papers on oral involvement of lymphoma were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2011 and Jan 2011-Jul 2025 in the analysis of research trends.

There were 557 relevant papers on lymphoma involving the oral cavity, with total citations of 7663 and the h index of 39. The most related type or subtype of lymphoma was non-Hodgkin lymphoma, followed by B cell lymphoma, large cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, T cell lymphoma. The most treatment keyword were cyclophosphamide, followed by doxorubicin, vincristine, prednisone, cancer chemotherapy, and cancer radiotherapy. The trend of clinical aspect has changed to retrospective study, diagnostic imaging, positron emission tomography-computed tomography (PET-CT), cervical lymph node, complication, osteolysis, and cytarabine after 2011. The trend of laboratory aspect has changed to cyclin D1, Bcl-6, syndecan-1, Ki-67, CD5, CD79a, metabolism, lactate dehydrogenase, tumor marker, and gene rearrangement.

This scientometric study for the first time elucidated the current scenario and research trends in the field of lymphoma involving the oral cavity, underpinning that stomatologists and dentists can play active roles in providing early recognition and timely diagnosis of this malignancy.