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Genome assembly and annotation of two clinical Naegleria fowleri isolates from Costa Rica

Nina Allouch1, Lissette Retana Moreira2,3, Nalhyte Aurago1

  • 1Institut Pasteur de la Guadeloupe, Les Abymes, Guadeloupe, France.

Microbiology Resource Announcements
|September 3, 2026
PubMed

Keywords:
Naegleria fowlerigenome annotationgenome assemblyprimary amebic meningoencephalitis

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Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.