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Updated: Sep 5, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Optical Coherence Tomography-Guided Directional Coronary Atherectomy Using Tip-Detection Method
Tomoaki Haga1, Akihito Tanaka2, Yosuke Tatami1
1Department of Cardiology, JA Aichi Koseiren Toyota Kosei Hospital, Toyota, Japan.
Abstract:
Directional coronary atherectomy (DCA) requires precise spatial orientation. Although the tip detection method is established for intravascular ultrasound, its application in optical coherence tomography (OCT)-guided DCA remains unestablished. We present a case of functionally significant stenosis at the left anterior descending (LAD) artery ostium treated with OCT-guided DCA. We adapted the tip detection method using a second guidewire with a tip curve. Aligning the fluoroscopically directed guidewire with the 3 o'clock position on the OCT cross-section achieved precise three-dimensional spatial co-registration, enabling accurate plaque localization. This first report demonstrates that OCT-guided tip detection offers a safe and sophisticated debulking strategy for complex coronary lesions.
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