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Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
Published on: May 18, 2022
Global evidence for bounded human lifespan growth
Marta Gonçalves1, Byung Mook Weon2
1School of Chemical Engineering and Global Research Center for e-Chem Meditronic Systems, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Abstract:
Is there a limit to human lifespan? We examine upper-tail lifespan dynamics in 46 countries using reliable period life-table data. The characteristic life ( ), the model-based upper-tail parameter ( ), and their interval ( ) are estimated annually from the 1990s onward. Across countries, increases steadily, whereas declines or stabilizes and narrows, a pattern consistent with postponed and increasingly concentrated late-life mortality rather than unlimited upper-tail expansion. Under the baseline projection model, both females and males approach years and years by 2100. Sensitivity analyses show that the inferred asymptotic boundary is model-dependent, so the projected value near 120 years should be interpreted as a mathematical upper-tail estimate rather than a definitive biological maximum. These findings are consistent with, but do not establish, an increasingly bounded upper-tail survival regime within the present demographic and modeling framework.
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