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MOSAIC: A flexible, software-agnostic workflow for montage cryo-ET
Jacob Jensen1, Luiza Mendonça1
1Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
Structure (London, England : 1993)
|September 3, 2026
Abstract:
In this issue of Structure, Hylton et al.1 present MOSAIC, an accessible, acquisition-software-agnostic framework for montage cryo-electron tomography (cryo-ET). By streamlining acquisition and stitching workflows, MOSAIC lowers technical barriers to wide-field imaging, maximizing data recovery from cryolamellae and making meso-scale cellular architecture broadly accessible across diverse cryo-ET platforms.
