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Published on: October 24, 2025
[WHO Guideline for the prevention, diagnosis and treatment of infertility]
Brigitte Piso1, Isolde Sommer2, Gerald Gartlehner2,3
1Department für Evidenzbasierte Medizin und Evaluation, Universität für Weiterbildung Krems, Krems, Austria.
Background:
Infertility affects approximately one in six people of reproductive age worldwide and represents a major global health issue, regardless of world region or income level. It limits the realization of individuals' desire to have children, thereby underscoring the importance of high-quality fertility care.
Method:
The guideline was developed by WHO in accordance with WHO standards. It. The executive summary was translated into German by the WHO Collaborating Centre for Evidence-based Medicine at the University of Continuing Education Krems (Austria).
Results:
In addition to general good practice recommendations for the management of infertility, the guideline includes four recommendations on prevention, eleven on diagnosis, and 24 on the treatment of infertility. The diagnostic and treatment recommendations further distinguish between female, male, and unexplained infertility.
Conclusions:
This guideline is the first WHO guideline on the prevention, diagnosis, and treatment of infertility. It aims to improve the implementation of evidence-based interventions related to infertility.
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