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Experimental maternal hyperphenylalaninemia: disaggregation of fetal brain ribosomes

J H Copenhaver, J P Vacanti, M J Carver

    Journal of Neurochemistry
    |August 1, 1973
    PubMed
    Abstract

    No abstract available in PubMed .

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    Inborn Errors of Metabolism01:20

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    Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...

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