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Published on: May 12, 2023
[Research advances on comprehensive utilization of non-medicinal parts of Coptis chinensis]
Ping Tang1, Yong Yang2, Min Yang3
1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China the First Affiliated Hospital of Chongqing University of Chinese Medicine, Institute of Traditional Chinese Medicine Preparations, Chongqing Traditional Chinese Medicine Hospital Chongqing 400021, China.
Abstract:
Non-medicinal parts(NMP) of Coptis chinensis are abundant but have long been discarded as agricultural waste, resulting in resource wastage and environmental pollution. Research indicates that NMP contains active components similar to those in rhizomes, including alkaloids, flavonoids, and phenylpropanoids. These components exhibit pharmacological activities such as hypoglycemic and lipid-regulating effects, antioxidant properties, and antibacterial activity, while demonstrating high safety profiles, offering broad development prospects. This review systematically summarized the chemical composition, pharmacological effects, safety evaluation, and current product development status of NMP, providing an in-depth analysis of their material basis and mechanisms of action. To address current limitations such as fragmented research and delayed product development, in the future, on the basis of further clarifying its material basis, efficacy, and safety, it is necessary to apply for legal identities for NMP, and thereby promote the resource utilization and sustainable development of NMP of Coptis chinensis.