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Two cases of repeated upper gastrointestinal bleeding due to chronic disseminated intravascular coagulation

Tomoko Terashita1, Hiroyoshi Iwagami2, Riki Sakano1

  • 1Department of Gastroenterology and Hepatology, Japanese Red Cross Wakayama Medical Center, 4-20, Komatsubaradori, Wakayama, 640-8558, Japan.

Clinical Journal of Gastroenterology
|September 4, 2026
PubMed

We describe two older patients with repeated bleeding due to gastric ulcers despite achieving endoscopic hemostasis. In both cases, laboratory tests suggested chronic disseminated intravascular coagulation, with an underlying aortic aneurysm identified as the cause of this bleeding. Both patients achieved successful hemostasis after supplementation with fresh frozen plasma, while surgical treatment of the underlying aneurysm was not feasible. Recurrent gastrointestinal bleeding warrants evaluation of coagulation abnormalities and screening for aortic pathology.

Keywords:
Aortic aneurysmChronic disseminated intravascular coagulationUpper gastrointestinal bleeding

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