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An Automated Method to Perform The In Vitro Micronucleus Assay using Multispectral Imaging Flow Cytometry
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GenoTox Cell Counter: A mobile App to standardize cell counting in genotoxicity testing
Gumercindo Pimentel-Peralta1,2, Yennifer Alfaro2,3, Juliana Da Silva1,2
1Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Genética e Biologia Molecular (PPGBM), Porto Alegre, RS, Brazil.
Abstract:
The analysis of genotoxicity assays has long posed a major challenge for the standardization of analyses in environmental and occupational settings, as well as in assessing health impacts across various diseases. In this context, we present a mobile application designed to facilitate and standardize scoring in micronucleus, comet, chromosomal aberration, and erythrocyte abnormality assays. The app offers a portable and intuitive interface that allows users to save, resume, and share counting sessions efficiently, supporting both laboratory and field settings. By digitizing the workflow, it enhances data organization, traceability, and time management while preserving the rigor of microscopic analysis. Its adoption offers a practical and reliable alternative to manual tallying, contributing to the evolution of genotoxicity testing practices through mobile technology.
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