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Updated: Sep 6, 2026

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions
Published on: February 24, 2021
The expanding role of Cav3 channels in glioblastoma
Maria Casals1, Judit Herreros1, Carles Cantí2
1Dpt Basic Medical Sciences, University of Lleida, Rovira Roure 80, 25198 Lleida, Spain; Calcium Cell Signaling, Institut de Recerca Biomèdica de Lleida - Fundació Dr. Pifarré, IRBLleida (ROR: 03mfyme49), Rovira Roure 80, 25198 Lleida, Spain.
Abstract:
Tumor-intrinsic voltage-gated Cav3 calcium channels, comprising the Cav3.1, Cav3.2 and Cav3.3 isoforms, have been implicated in cancer cell proliferation and survival. Recent work by Dube et al. reveals a role for microenvironmental Cav3.2 channels in glioblastoma, promoting neuron-cancer cell crosstalk and identifying changes in immune-related programs associated with Cav3.2 deficiency.
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