Direct clinician-pathologist multidisciplinary review and diagnostic revision in children with gastrointestinal...

Accurate pediatric gastrointestinal (GI) diagnosis often depends on integrating clinical, endoscopic, and histopathologic information. We evaluated the impact of weekly face-to-face multidisciplinary team (MDT) meetings on diagnosis in children undergoing endoscopy or liver biopsy at a tertiary center. This single-center study included 53 patients discussed between March and November 2025; because 6 children were reviewed twice, the analysis was case-based (59 MDT discussions). Diagnostic change was defined as any revision, reclassification, refinement, or exclusion of a suspected diagnosis after MDT review. Overall, diagnosis changed in 12 of 59 cases (20.3%). Endoscopic classifications changed significantly after MDT discussion (p = 0.0091), as did histopathology classifications (p = 0.0118). Pathologist experience was associated with pathology revision (p = 0.0293), whereas patient-specific parameters and endoscopist experience were not. Endoscopy requests to pathology were frequently sparse. These findings suggest that regular clinician-pathologist MDT review can improve diagnostic precision in pediatric GI practice.