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Evidence of Chikungunya Virus Reinfection in Two Patients With Lupus During the 2024-2025 Outbreak on Reunion Island
Anissa Desmoulin1,2, Dimitri Kornblum1,2, Marie-Christine Jaffar-Bandjee3
1Service de Maladies Infectieuses et Tropicales, CHU de La Réunion Sites Sud, Saint Pierre, La Réunion, France.
Abstract:
Chikungunya virus infection is considered to confer prolonged immunity. During the 2024-2025 outbreak in Reunion Island, we identified a confirmed and a probable reinfection in patients with systemic lupus erythematosus. These findings challenge this paradigm, underly a complex pathophysiology, and suggest that reinfection may occur, particularly in specific populations.
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