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Updated: Sep 7, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
A Scandinavian perspective of the projected lifetime cost-effectiveness of rivaroxaban plus aspirin in the COMPASS
Andre Lamy1, Lars Ryden2, Wesley Tong1
1Population Health Research Institute, McMaster University, Hamilton, Canada.
Abstract:
Objectives. Rivaroxaban 2.5 mg twice daily with aspirin 100 mg daily was superior to aspirin 100 mg daily in the COMPASS trial but the cost-effectiveness in Scandinavia is unknown. Design. Mean lifetime costs (USDs) and quality-adjusted life-years were determined from a Scandinavian perspective using a 2-state Markov model with US mortality data. Subgroup and sensitivity analyses were performed. Results. Over a lifetime adding rivaroxaban to aspirin had lower costs (-$3791USD/-23675DKK/-27410NOK/-29200SEK) and gained 1.17 QALYs versus ASA alone. Conclusion. Rivaroxaban 2.5 mg twice daily with aspirin is a dominant strategy compared to aspirin alone in COMPASS participants from a Scandinavian perspective.
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