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BREAST-V Versus MRI for Breast Volume Assessment Before and After Breast Asymmetry Surgery: Good Preoperative
José Renato Nahlous Ferreira Leite1, Mayara Mytzi de Aquino Silva1, Juan Carlos Montano Pedroso1
1Postgraduate Program in Translational Surgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
Background:
Objective breast volume measurement is critical for breast asymmetry surgery. BREAST-V is a practical anthropometric formula, but its interchangeability with MRI, particularly after surgery, is unclear.
Objectives:
To evaluate agreement between BREAST-V and MRI before and after breast asymmetry surgery.
Methods:
Forty patients underwent preoperative and postoperative MRI and BREAST-V assessments. Agreement was evaluated using ICC, Bland-Altman analysis, and error metrics. Intraoperative field changes were recorded, an MRI-based MCID was derived using distribution-based methods, and satisfaction was assessed with BREAST-Q.
Results:
Preoperatively, BREAST-V showed good association and moderate agreement with MRI (ICC = 0.788; r = 0.840; p < 0.001). Postoperatively, agreement was poor (ICC = 0.210; r = 0.339; p = 0.032). Bland-Altman bias increased from +69.5 mL preoperatively to +279.2 mL postoperatively, with wide limits of agreement (-366.4 to +505.5 mL and -67.2 to +625.7 mL, respectively). Error metrics showed clinically relevant divergence, particularly postoperatively (mean absolute error, 177.6 vs 280.5 mL; mean absolute percentage error, 35.5% vs 41.0%). The MRI-derived MCID for asymmetry was 92.5 mL. Among 30 patients with paired BREAST-Q data, Satisfaction with Breasts improved from 25.0 ± 24.1 to 81.0 ± 12.7 points (mean improvement, 56.0; 95% CI, 46.4-65.6; p < 0.001).
Conclusions:
BREAST-V may be useful for preoperative planning but should not be considered interchangeable with MRI after surgical remodeling.
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