Related Experiment Video
Updated: Sep 8, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Exploring the Links between Individual Types of Adverse Childhood Experiences and Self-Reported Psychiatric and
Colleen M Ray1, Kayla N Anderson1, Megan Kearns1
1Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS 106-10, Atlanta, GA 30341 USA.
Abstract:
Adverse childhood experiences (ACEs) are associated with poor mental health outcomes, but less is known about how specific ACEs are associated with certain outcomes, particularly beyond depression and anxiety. This study explores how fourteen individual types of ACEs are associated with seven self-reported psychiatric and neurocognitive conditions (PNC), including depression, anxiety, post-traumatic stress disorder, oppositional defiant disorder/conduct disorder (ODD/CD), antisocial personality disorder, borderline personality disorder (BPD), and traumatic brain injury (TBI). This exploratory study uses self-reported cross-sectional data obtained from a convenience sample of adult Amazon's Mechanical Turk workers (n = 1,184). We conduct a series of regressions to estimate adjusted prevalence ratios for each individual ACE and with the seven PNC outcomes. Results indicate nearly all individual ACEs were associated with each outcome. Seeing someone shot or stabbed was associated with a 12-fold increase in ODD/CD, and experiencing emotional abuse was associated with a nearly 22-fold increase in BPD. Ordinal measurement, which captured frequency of ACE exposure, was especially important in understanding the dose-relationship between ACE exposure and TBI. The main limitations of this work lie in the data quality, which is affected by low prevalence rates of some of the outcomes and the use of a convenience sample. This research builds on previous work identifying links between ACEs and PNC by identifying relationships between individual types of ACEs and a number of PNC, including depression and anxiety. Results support understanding of the effects of specific childhood traumas on PNC, which may improve intervention and response efforts.
Related Concept Videos
Psychological and Sociocultural Causes of Schizophrenia
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Sources of Self-Esteem I: Family Experience
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...

