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Updated: Sep 9, 2026

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
Published on: October 31, 2012
Generation of high-quality reference control panels of human induced pluripotent stem cell clones from PBMCs
Elisabeth Stein1, Ellen Mosca1, Jiss John1
1Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
Abstract:
High-quality, standardized iPSC reference lines are crucial for disease modeling and regenerative medicine. We generated and extensively characterized thirteen iPSC clones from PBMCs of five healthy donors (three female, two male) using non-integrating Sendai virus. This resource is distinguished by its standardized derivation and deep characterization and the deliberate generation of multiple clones per donor to capture and control for clonal variation. These validated lines are available to academic and commercial researchers to accelerate advances in stem cell biology and tissue engineering.
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