Related Experiment Video For Fatty liver
Updated: Sep 9, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
Published on: July 19, 2024
Metabolic signatures in metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma
Wen-Jie Fan1, Yu-Mei Wu2, Xing-Yu Liu2
1Department of Radiation Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Abstract:
Hepatocellular carcinoma (HCC) is a common and lethal malignancy, with an increasing incidence globally, which is partially attributed to the rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD). Complex metabolic rearrangements occur in MASLD-related HCC (MASLD-HCC) to promote the initiation and development of cancer. Nevertheless, comprehensive understanding of the metabolic transformations during the progression from MASLD to HCC remains limited. In this review, we introduce recent advances characterizing the metabolic changes in MASLD-HCC, thereby offering potential directions and clues for further studies.
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