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Updated: Sep 9, 2026

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
A Predictive Imaging Model for Cervical PAS in Complete Placenta Previa Using Combined Ultrasound and MRI
Zhiyi Yang1, Peiran Yang1, Jun Yan1
1Department of Obstetrics and Gynecology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, Jiangsu, 215002, People's Republic of China.
Objective:
To develop and validate a combined ultrasound-MRI predictive imaging model for diagnosing cervical placenta accreta spectrum (PAS) in women with complete placenta previa.
Study Design:
This retrospective study included a total of 350 patients with complete placenta previa who underwent comprehensive prenatal ultrasound and MRI examinations; independent imaging predictors were identified using multivariate logistic regression; Two internal validation methods were employed: a 7:3 cohort split and 1000 bootstrap resamples. The model's diagnostic performance was comprehensively evaluated using a combination of ROC curves, calibration curves, and decision curve analysis (DCA).
Results:
Five independent risk factors were identified: abundant cervical blood flow, cervical sinus, lacunae over the cervix, cervical length <3.0 cm, and placental heterogeneity. The combined model yielded an AUC of 0.892, sensitivity of 87.603%, and specificity of 81.489%. The AUC on the internal validation set reached 0.889; the model demonstrated good discriminatory power and calibration, and showed considerable clinical net benefit across a wide range of risk thresholds. Patients with cervical PAS had significantly higher rates of adverse maternal-fetal outcomes.
Conclusion:
A predictive model combining five key ultrasound and MRI features shows high diagnostic performance for cervical PAS in complete placenta previa, supporting preoperative risk stratification and surgical planning. This study is a single-center retrospective analysis; it is subject to selection bias and does not include a multicenter external cohort to support its generalizability. Further validation of the model's clinical utility requires large-sample, multicenter prospective cohort studies.
