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Published on: December 9, 2022
Patient-reported outcome measures after revascularization for intermittent claudication from the GermanVasc
Frederik Peters1, Mette Søgaard2, Jenny Lübcke3
1Hamburg Cancer Registry Hamburg, Hamburg, Germany; German Institute for Vascular Research, Berlin, Germany.
Objective:
This prospective multicenter cohort study investigated patient-reported outcome measures in patients undergoing invasive revascularization for intermittent claudication at 35 centers in Germany.
Methods:
Patients were enrolled between May 1, 2018, and March 31, 2021, and followed for up to 12 months (NCT03098290). The Physical Component Summary score (PCS-12) of the SF-12 questionnaire, maximum pain-free walking distance, and frequency of leg pain at rest were collected as outcomes.
Results:
A total of 963 (64% male; median age, 68 years) provided sufficient data at follow-up (median, 352 days). At index admission physical quality of life was substantially impaired at a median PCS-12 score of 35 (Q1: 28; Q3: 43). At follow-up, median PCS-12 improved to 45 (Q1: 39; Q3: 52) along with substantial improvement in maximum walking distance (+20 minutes) and lower leg pain (-10 points). Not working, retired job, and obesity were associated with lack of improvements in PCS-12 during follow-up, whereas obesity and retired job seemed to particularly prevent improvements in maximum walking distance and reductions in leg pain.
Conclusions:
Invasive revascularization with either technical approach markedly improved patient-reported outcome measures. Gains were smaller in obese and retired patients, with similar trends in those not working and those with a high comorbidity burden.
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