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Updated: Sep 10, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Anemia of Inflammation in Solid Tumor Patients and Practical Education for Oncologists and Nurses
Xiaoyan Si1, Xiaomin Wei1, Xiaoyan Liu1
1Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Abstract:
Anemia is prevalent in patients with cancer, and anemia of inflammation (AI) is a common pathophysiological type. AI is mainly characterized by functional iron deficiency. This review summarizes the current knowledge regarding the epidemiology, clinical manifestations, molecular mechanisms, diagnostic criteria, and therapeutic advancements in cancer-related AI. It focuses on the central role of interleukin-6 (IL-6) and the emerging therapeutic strategies targeting the IL-6-hepcidin-ferroportin axis. Additionally, this review integrates practical educational content designed for oncologists and nurses to enhance their clinical competence in recognizing, diagnosing, and managing AI; it is essential to alleviate the symptom burden and improve the quality of life of patients with cancer.
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