Topical Treatment With Clindamycin for Confluent and Reticulated Papillomatosis in a Pregnant Woman

Confluent and reticulated papillomatosis (CARP) is a rare skin condition that typically shows an effective response to oral minocycline. In this case, we offer support for an alternative therapy with topical clindamycin and glycolic acid for seven weeks, leading to full resolution of CARP in a gravida 2 para 1 woman in her first trimester of pregnancy. Limited evidence exists of topical therapies suitable for use in pregnant individuals without underlying contraindications. Pregnancy limits the use of tetracyclines and retinoid therapies. Therefore, topical clindamycin and glycolic acid offer a low-risk treatment, expanding upon the available options for non-systemic therapies in the management of CARP.