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Published on: June 8, 2017
Evaluation of reflexive, hearing-targeted congenital cytomegalovirus screening at a high-volume center
Kristina Thompsen1, Malika Shah2, Joseph Fishbein3
1Division of Neonatology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. kthompsen@luriechildrens.org.
Objective:
Examine congenital cytomegalovirus (cCMV) testing practices before and after implementation of a hospital-wide, reflexive, hearing-targeted screening policy.
Study Design:
91079 infants from 2016 to 2023 were included retrospectively from our center. cCMV testing and diagnosis rates were compared before and after implementation of a provider cCMV education program and policy automating a nursing order for cCMV test prior to discharge after referred NBHS.
Result:
The proportion of infants with referred NBHS who underwent cCMV screening increased after implementation compared to prior (7.7% versus 95.2%, p < 0.0001). cCMV screening for non-hearing-related cCMV indicators also increased (0.9% versus 3.3%, p < 0.0001). cCMV positivity rates prior to and after implementation were 0.015% and 0.036%, respectively (p = 0.053).
Conclusion:
This hospital-wide, reflexive, hearing-targeted screening policy was associated with significantly improved cCMV screening rates and may enhance early cCMV detection, supporting standardized hospital-specific protocols and education to implement state mandates.
