Association between polycystic ovarian syndrome and psychiatric morbidity in a rural setting: A cross-sectional study

Polycystic ovarian syndrome (PCOS) is the most common endocrine-metabolic condition affecting women in reproductive years. Women with PCOS often face psychiatric issues such as anxiety, depression, low self-esteem, negative body image, and eating disorders, which can worsen quality of life and pose treatment challenges. Despite its prevalence, psychiatric aspects are often overlooked.

To assess depression, anxiety, stress, and quality of life in women with PCOS.

It is a cross-sectional study conducted for 18 months. The sample includes 102 patients who are diagnosed with PCOS. The socio-demographic questionnaire, Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Anxiety Rating Scale (HAM-A), Perceived Stress Scale (PSS), WHO Quality of Life-Brief (WHOQOL-BREF), and Mini International Neuropsychiatric Interview (MINI) scales were used. Statistical analysis was done using the R language.

Mild depression was seen in 49%, and moderate in 48% on MADRS in women with PCOS. Mild anxiety was in 26.47%, moderate in 27.45% on HAM-A. Mild and moderate stress levels were seen in 31.37% and 68.62% on PSS. WHOQOL-BREF scores: domain 1 is 53.5, domain 2 is 42.8, domain 3 is 57.7, and domain 4 is 58.8, showing low scores, indicating a lower quality of life among women with PCOS.

There is an increased level of depression, stress levels, anxiety, and a low quality of life in all the domains, on the WHOQOL-BREF scores, among women with PCOS.