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Updated: Sep 13, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
Published on: April 11, 2018
A computer vision-based modeling pipeline to facilitate efficient video-to-strain analysis of human tibia during
Xin-Sheng Xu1, Jia-Xing Zhang2, Xuan Guo1
1Institute of Trustworthy Embodied Artificial Intelligence, Fudan University, 220 Handan Road, Shanghai, 200433, China; Biomech-X Laboratory, Fudan University, 220 Handan Road, Shanghai, 200433, China.
Background And Objective:
Tibial stress and strain are crucial indicators of bone health and injury risk, yet their estimation with conventional marker-based motion capture systems is time-consuming and constrained to multi-camera laboratory setups, limiting broader applicability.
Methods:
We propose a novel video-to-strain analysis (V2S) method, enabling subject-specific musculoskeletal modeling and tibial stress/strain computation from single-view smartphone recordings of treadmill walking. Markerless motion was reconstructed using SMPL-based fitting with HuMoR, a deep generative human motion prior, together with PlaneRCNN ground-plane estimation and contact and bilateral symmetry constraints to yield more stable 3D pose and gait reconstruction from single-view camera. Feasibility was evaluated by comparing kinematics, muscle forces, and finite element-computed tibial stress/strain against a marker-based reference workflow.
Results:
Compared to the marker-based method, the proposed markerless method yielded joint kinematics with R2 = 0.86 and muscle forces with R2 = 0.81. Relative to the baseline HuMoR model, our approach achieved lower kinematic errors (hip, knee, and ankle RMSE of 3.6°, 4.8°, and 4.0°, compared with 9.1°, 11.6°, and 12.3° for HuMoR). The model-computed results with peak von Mises stress varying by 3.8% and the maximum principal strain differing by 11.9%, with the largest discrepancies occurring in stance-phase.
Conclusions:
Single-view markerless approach offers a practical alternative for efficient motion and bone strain analysis, where marker-based motion capture is not feasible.
